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KMID : 0370920130300020152
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Yeungnam Univercity Journal of Medicine
2013 Volume.30 No. 2 p.152 ~ p.155
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A Case of Metastatic Hepatocellular Carcinoma of the Orbit
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Yang Young-Joo
Bae Seung-Hyeon
Jang Il-Young
Jun Mi-Jung
Jung Ji-Won
An Ji-Hyun
Shim Ju-Hyun
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Abstract
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Orbital metastasis from hepatocellular carcinoma is very rare, with only 14 biopsy-proven cases from hepa tocellular carcinoma cases reported in English literature and three cases reported in Korea. Common symptoms of orbital metastasis are proptosis, visual loss, ocular pain and oculomotor dysfunction. For its precise diagnosis, we can perform fine needle aspiration biopsy, orbit CT or MRI, and ultrasonography. Radiotherapy is the mainstay in the treatment of orbital metastasis. In addition, chemotherapy, hormonal therapy and surgical intervention can play a role in the treatment of orbital metastasis according to the primary cancer and symptoms. However, the prognosis of orbital metastasis is poor. We report herein a rare case of a patient with orbital metastasis from hepatocellular carcinoma, which was treated with various modalities that included resection, and who had good clinical and radiological responses to radiation therapy
and sorafenib (Nexavar, Bayer HealthCare).
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KEYWORD
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Eye neoplasm, Hepatocellular carcinoma, Metastasis, Radiotherapy, Sorafenib
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